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Johns Hopkins Ion Channel Center (JHICC)
School of Medicine
733 North Broadway, BRB 311
Baltimore, MD 21205
Tel: 410-614-3692
Fax: 410-614-1001
Email inquiry: alison_neal@jhicc.org |
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NEWS
Dr. Owen McManus joins Johns Hopkins Ion Channel Center as director of operations. Dr McManus is a seasoned industrial ion channel expert who had worked with Merck for 21 years. He has extensive experience in ion channel drug discovery, technology development, and project integration in multiple therapeutic areas. At Merck, he led basic research teams at multiple discovery stages, including target identification and validation, assay development, HTS setup, lead identification and optimization, and technology development. |
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Welcome…
The Johns Hopkins Ion Channel Center (JHICC) was founded in late 2008 with an award from the National Institute of Health (NIH). As part of NIH’s strategic funding plan, JHICC is focusing on developing small molecular probes for ion channels and transporters. Ion channels are important protein targets, both for drug development and for understanding basic physiology. They are, however, traditionally difficult targets to investigate by high throughput approaches. The six-year funding initiative from NIH gives JHICC the support to perform high-throughput screens and to continue technological development for ion channels and transporters. We have completed several large scale (more than 300,000 compounds) primary screens and the data are available from PubChem (hERG (AID:1511), Kir2.1 (AID:1672), Kv7.2 (AIDs: 2156 & 2239) and TrpC4 (AIDs:2227, 2237 & 2247). JHICC investigators are very much interested in and looking forward to the opportunity to work with you on channels and transporters of importance to your research.
Min Li, Director, JHICC
minli@jhmi.edu
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